CYP2D6 antibody

References #8
Category:
Catalogue No.: 
FNab02157
Alias: 
Cytochrome P450 2D6|CYPIID6|Cholesterol 25-hydroxylase|Cytochrome P450-DB1|Debrisoquine 4-hydroxylase|CYP2D6|CYP2DL1 antibody
Gene Name: 
CYP2D6
UniProt ID: 
P10635
Size Price
100μg Inquiry
Dispatch Time: About 3 working days
Contact Us
Product Name
CYP2D6 antibody
Catalogue No.
FNab02157
Gene Name
CYP2D6
UniProt ID
P10635
Alias
Cytochrome P450 2D6|CYPIID6|Cholesterol 25-hydroxylase|Cytochrome P450-DB1|Debrisoquine 4-hydroxylase|CYP2D6|CYP2DL1 antibody
Isotype
IgG
Form
liquid
Purification
Immunogen affinity purified
Immunogen
cytochrome P450, family 2, subfamily D, polypeptide 6
Recommended dilution
WB: 1:1000-1:5000; IHC : 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.


Figures for this product are not available in this catalogue.

Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Dispatch Time
About 3 working days
Ordering & Delivery
How do I place an order?
Use the Inquiry button on this page or write to tekintolga89@gmail.com. Include the catalogue number and the quantity you need.
What is the dispatch time?
In-stock items are dispatched within 1-3 business days. Items that need to be produced take longer; we confirm the date when you order.
Do you ship outside Türkiye?
Shipping is arranged case by case. Contact us with the destination and we will quote carriage and lead time.
Storage & Handling
How should an unopened kit be stored?
At 2-8 °C unless the datasheet says otherwise. Do not freeze a kit that is not marked for freezing.
How long is an opened kit stable?
It depends on the component. The Kit Components table on this page lists the storage condition for each item after opening.
What should I do if the shipment arrives warm?
Photograph the package and contact us the same day. Do not use the kit until we have confirmed it is still within specification.
Assay Questions
Which sample types can I use?
The Sample Type row in the specifications above lists the validated matrices for this product. Other matrices need validation on your side.
My background is too high. What should I check?
The usual causes are insufficient washing, contaminated buffers, or too much detection antibody. Our Protocol pages cover the full troubleshooting sequence.
Can I run fewer wells than the kit provides?
Yes. Dismountable microplates let you use part of a plate and reseal the rest with the desiccant supplied.
Technical Support
Something did not work. What do you need from me?
Send the catalogue number, the lot, your protocol deviations and the raw OD values. That is usually enough to identify the cause.
Do you provide a certificate of analysis?
Yes, per lot. Ask for it with the catalogue number and lot number.

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Cited Publications (8)

The novel third-generation antipsychotic drug brexpiprazole affects hepatic transcription factors, serum hormone levels, and cytochrome P450 enzymes after prolonged treatment: pharmacological significance IF: 3.8

Pharmacological Reports · 2026-05-22

The Effect of Maternal High-Fat or High-Carbohydrate Diet during Pregnancy and Lactation on Cytochrome P450 2D (CYP2D) in the Liver and Brain of Rat Offspring IF: 4.9

International Journal of Molecular Sciences · 2024-09-06

Molecular Mechanisms of the Regulation of Liver Cytochrome P450 by Brain NMDA Receptors and via the Neuroendocrine Pathway—A Significance for New Psychotropic Therapies IF: 5.6

International Journal of Molecular Sciences · 2023-12-08

The Effect of the Selective N-methyl-D-aspartate (NMDA) Receptor GluN2B Subunit Antagonist CP-101,606 on Cytochrome P450 2D (CYP2D) Expression and Activity in the Rat Liver and Brain IF: 6.208

International Journal of Molecular Sciences · 2022-11-18

The Atypical Antipsychotic Lurasidone Affects Brain but Not Liver Cytochrome P450 2D (CYP2D) Activity. A Comparison with Other Novel Neuroleptics and Significance for Drug Treatment of Schizophrenia IF: 7.666

Cells · 2022-11-11

Chronic treatment with asenapine affects cytochrome P450 2D (CYP2D) in rat brain and liver. Pharmacological aspects IF: 3.921

Neurochemistry International · 2022-03-04

Long-Term Treatment with Atypical Antipsychotic Iloperidone Modulates Cytochrome P450 2D (CYP2D) Expression and Activity in the Liver and Brain via Different Mechanisms IF: 6.6

Cells · 2021-12-17

Cytochrome P450 2D (CYP2D) enzyme dysfunction associated with aging and serotonin deficiency in the brain and liver of female Dark Agouti rats IF: 3.921

Neurochemistry International · 2021-11-19

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