RBBP8 antibody

Category:
Catalogue No.: 
FNab07153
Alias: 
DNA endonuclease RBBP8|CtBP-interacting protein (CtIP)|Retinoblastoma-binding protein 8 (RBBP-8)|Retinoblastoma-interacting protein and myosin-like (RIM)|Sporulation in the absence of SPO11 protein 2 homolog (SAE2)|RBBP8|CTIP antibody
Gene Name: 
RBBP8
UniProt ID: 
Q99708
Size Price
100μg Inquiry
Dispatch Time: About 3 working days
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Product Name
RBBP8 antibody
Catalogue No.
FNab07153
Gene Name
RBBP8
UniProt ID
Q99708
Alias
DNA endonuclease RBBP8|CtBP-interacting protein (CtIP)|Retinoblastoma-binding protein 8 (RBBP-8)|Retinoblastoma-interacting protein and myosin-like (RIM)|Sporulation in the absence of SPO11 protein 2 homolog (SAE2)|RBBP8|CTIP antibody
Isotype
IgG
Form
liquid
Purification
Immunogen affinity purified
Immunogen
retinoblastoma binding protein 8
Recommended dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Endonuclease that cooperates with the MRE11-RAD50-NBN(MRN) complex in processing meiotic and mitotic double-strand breaks(DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining(A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations.


Figures for this product are not available in this catalogue.

Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Dispatch Time
About 3 working days
Ordering & Delivery
How do I place an order?
Use the Inquiry button on this page or write to tekintolga89@gmail.com. Include the catalogue number and the quantity you need.
What is the dispatch time?
In-stock items are dispatched within 1-3 business days. Items that need to be produced take longer; we confirm the date when you order.
Do you ship outside Türkiye?
Shipping is arranged case by case. Contact us with the destination and we will quote carriage and lead time.
Storage & Handling
How should an unopened kit be stored?
At 2-8 °C unless the datasheet says otherwise. Do not freeze a kit that is not marked for freezing.
How long is an opened kit stable?
It depends on the component. The Kit Components table on this page lists the storage condition for each item after opening.
What should I do if the shipment arrives warm?
Photograph the package and contact us the same day. Do not use the kit until we have confirmed it is still within specification.
Assay Questions
Which sample types can I use?
The Sample Type row in the specifications above lists the validated matrices for this product. Other matrices need validation on your side.
My background is too high. What should I check?
The usual causes are insufficient washing, contaminated buffers, or too much detection antibody. Our Protocol pages cover the full troubleshooting sequence.
Can I run fewer wells than the kit provides?
Yes. Dismountable microplates let you use part of a plate and reseal the rest with the desiccant supplied.
Technical Support
Something did not work. What do you need from me?
Send the catalogue number, the lot, your protocol deviations and the raw OD values. That is usually enough to identify the cause.
Do you provide a certificate of analysis?
Yes, per lot. Ask for it with the catalogue number and lot number.

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